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KMID : 0384119930130040595
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Korean Journal of Clinical Pathology
1993 Volume.13 No. 4 p.595 ~ p.600
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A Case of Mixed Cell Type of B Cell Chronic Lymphocytic Leukemia
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Abstract
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Chronic lymphocytic leukemia (CLL) is a disease of considerable clinical and morphologic diversity. The FAB group defined CLL cases showing prolymphocytic transformation as ″mixed cell type of CLL ″and classified into two groups: one is CLL/PL
type
with 10-55% of prolymphocytes and the other showing a spectrum of cells from small to large lymphocytes with tendency to cytoplasmic basophilia and less than 10% of prolymphocytes in peripheral blood. We report a case of mixed cell type of CLL,
belonging to CLL/PL type The patient was a 70-year-old temale, showing marked lymphocytosis (WBC 180,000/μl, lymphocytes 98%), of which 37% was prolymphocytes. The immunophenotype was B cell CLL : CD5, CD19, CD20, HLA-DR and SmIg positive.
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